Sakarya University Training and Research Hospital, Department of Neurology, Assoc. Dr. Yesim Güzey Aras, April 11 is World Parkinson’s Disease Day.He made special statements in.
Sharing up-to-date information about the disease on World Parkinson’s Disease Day, Assoc. Dr. Jade Güzey Aras 150-200 thousand in Turkey and in the world that more than 10 million patients with Parkinson’s disease and said the number would reach 30 million by 2030.
Stating that Parkinson ranks first among the diseases that are the reason for admission to the movement disorders outpatient clinic, Assoc. Dr. Aras stated that there is no definitive treatment yet to completely repair the damage in brain cells, but the symptoms can be significantly reduced with the right treatment.
“ FINDINGS BEGIN 20 YEARS AGO ”
Referring to the findings of the disease, Assoc. Dr. Aras said, “Movement disorder diseases are a progressive disease group that causes the brain cells to communicate with each other by damaging the region that produces the substance called dopamine. Dopamine is responsible for the control, harmony and fluency of movements in the brain. Symptoms of the disease occur when 70-80 percent of dopamine-producing cells are damaged. Parkinson’s disease is also the most common neurodegenerative (with loss of brain cells) progressive disease after Alzheimer’s disease. In fact, neurodegeneration begins 20 years before Parkinson’s symptoms appear. The first symptoms of the disease are tremors, which are often seen in the fingers of the hand, slowdown in movements, inability to turn in bed, dullness in facial expression and deterioration in handwriting.
“ THERE ARE THREE STAGES ”
Explaining the stages of Parkinson, Assoc. Dr. Aras said, “The disease is divided into three stages as mild, moderate and advanced according to clinical findings. In the mild stage, the patient is fully independent and can carry out daily tasks and self-care without the need for someone else’s help. In the middle stage, patients need help with some daily life activities (such as shopping, housework, cleaning) and self-care (shaving, bathing) skills. In the advanced stage, the patient needs help in almost all daily living activities and self-care skills. In addition to the findings of Parkinson’s disease at this stage, dementia (forgetfulness) and hallucinations may accompany him. ”
” EVERY TITRATION IS NOT PARKİNSON ”
Stating that in healthy people, there may be temporary tremors in the hands and legs due to stress, Assoc. Dr. Aras, ” Apart from this, tremors may occur in people with overworking thyroid gland, severe liver diseases and during the use of some medications. Therefore, not all tremors are Parkinson’s. The difference of tremor seen in Parkinson’s from others is that it occurs not in motion but at rest. Tremor specific to Parkinson’s disease may occur as the first sign of the disease in 50-75 percent of patients. However, tremors may not be seen during the course of the disease in 25-30 percent of patients. It is a detailed history taken from the patient and their relatives and a neurological examination to be performed by a physician specialized in movement disorders that will confirm the diagnosis. ”
Providing information about treatments, Assoc. Dr. Aras said, “Device-aided treatments such as brain pacemakers, navel pins, and tube insertion into the stomach are also widely used in our country. These treatments greatly benefit the symptoms seen in the advanced stage. For example, in the Duodopa method, which we apply in Sakarya University Training and Research Hospital, popularly known as gastric tube therapy, the patient is given a continuous infusion of medication through a tube inserted into the stomach and sent to the small intestine. Thus, drug and food interactions are prevented, the drug is provided to reach the brain rapidly, and studies on new drugs that can be used in the near future are also ongoing. In addition, experimental studies such as gene therapy, stem cell transplantation and vaccination continue. ”
THESE DISEASES MAY BE AWARE
Assoc. Dr. Aras ended his words as follows: “Symptoms such as constipation, depression, decreased sense of smell or inability to smell, mobility during sleep and speech while in REM sleep, vision problems, shoulder pain can be considered as harbingers of Parkinson’s disease. Apart from Parkinson’s disease, there are several different diseases such as Multiple System Atrophy, Dementia with Lewy Bodies, Corticobasal Degeneration, which can present with similar signs and symptoms and are called Parkinsonism. Although these diseases initially mimic all findings seen in Parkinson’s disease, they are recognized by adding different symptoms to the table over the years. However, in the early stage, it is not possible to distinguish these diseases from Parkinson’s disease by clinical examination, laboratory and imaging methods.
The green pods and leaves of the broad bean contain the substance Levodopa. With the Levodopa preparation we use in the treatment of Parkinson’s, if the peels or leaves of the broad bean are eaten, the effectiveness of the drug increases and more dopamine is released in the brain. This causes involuntary movements in the face, neck or limbs of the patient. ”