Kocaeli University Covid-19 Laboratories Responsible Prof. Dr. Aynur Karadenizli pointed out that the corona virus known as SARS CoV2 has had about 5 thousand mutations so far, and stated that good mutations have emerged in large pandemics in the future, but the Covid-19 virus has not reached this stage yet.
The corona virus, which has affected the whole world for more than a year, has recently mutated and increased its contagiousness. In particular, in the mutated corona virus cases that occurred in England, South Africa and Brazil, contagiousness increased by 70 percent.
assessment of mutant viruses that are seen in Turkey in Kocaeli University Faculty of Medicine, Department of Medical Microbiology, Faculty Member and Kocaeli University Lecturer Prof. Laboratories Covidien-19 Dr. Aynur Karadenizli said that mutation is a normal condition inherent in all viruses. Noting that the corona virus, known as SARS CoV2, has had approximately 5 thousand mutations so far. Dr. Black Sea people stated that good mutations emerged in the future in large pandemics, but the Covid-19 virus has not yet reached this stage.” COVID-19 ACTUATOR HAS PASSED APPROXIMATELY 5 THOUSAND MUTATIONS SO FAR ”
Prof. Dr. Karadenizli said, “Since last March, the pandemic has become the problem of our country. It is a big problem all over the world and we are still experiencing it. Mutations have come to the fore for the last 3-4 months. Because viruses constantly mutate. SARS CoV2, that is, the Covid-19 factor, is up to now. But these were mutations that did not have much effect on patients. We saw the effect of the mutation detected in the last September, especially in England. The mutant virus in England is 70 percent more contagious than the normal virus. The virulence, in other words, its disease-causing effect is not very high.As a result of its contagiousness, the number of infected patients increases too much, healthcare institutions are filled with patients and if there are many patients, of course, a certain percentage of them are seriously ill and intensive care is full. These mutant viruses cause health system overload and extreme fatigue. The lights have been working in great fatigue for about a year. This is a big problem, “he said.
“ IN BIG PANDEMIES, THERE WILL CHANGES FOR THE GOOD TIMES ”
Noting that mutations are natural events in the structure of viruses, Prof. Dr. Karadenizli continued as follows:
“Mutations are actually an action in the general structure of viruses. Continuous mutation occurs. Let’s think of it this way, a job is done in a factory and small changes occur at that time. Likewise, when viruses reproduce in the cell, mistakes occur at many points. These sometimes happen in a good way. In fact. In large pandemics, there will be positive changes in the future and then the virus becomes very low in disease-causing effect. Humanity also gets rid of this factor. But we have not reached these stages yet. In a good sense, there are some mutations. But the mutation that is dominant now is very good. We call them mutant strains. There are currently 3 mutations, namely England, South Africa and Brazil. Another mutation may occur tomorrow. We hope that we will encounter good mutations and the rate of spread of the disease is also reduced. There has been a further facilitation in the cell entry mechanism, a feature that greatly increases contagion. . Some mutations, especially those in South Africa, have slightly different characteristics than those in England. Contagiousness is high in this too. In some vaccination studies, ‘Is there resistance against antibodies formed?’ The question came up. This created great fear. At this point, we know that studies on RNA vaccines have not shown a major reduction in effectiveness. We do not have a problem with the use of these vaccines for now. We use Chinese vaccine widely in our country. There is no large study on the Chinese vaccine yet. “
” FIRST, WE DO PCR TEST, THEN WE GO TO MUTANT ANALYSIS ”
Emphasizing the importance of quarantining the close environment and contacts when a mutated virus is detected in a person, Prof. Dr. Aynur Karadenizli said, “When we detect a mutant virus, the close environment and contacts of the person with that mutant virus must be isolated. Therefore, we attach great importance to the detection of the mutation. For this, we need to do a fillation study about the cases we find positive in these mutant viruses. We inform the provincial directorate of health and in this way, fillation studies have been started. The citizen on the street says, ‘Do I have a mutant virus or not?’ “First of all, he has to have a complaint. If there are classical findings such as fatigue, cough and fever related to Covid-19, we first look at whether there is a virus in this person with the PCR test. Then we switch to mutation analysis.”
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